Master's Degree in Clinical Laboratory Sciences
Master of Science in Clinical Laboratory Sciences
A program that prepares specialists in the sub-specialties of clinical laboratory sciences, provides proficiency in medical diagnosis, and offers an environment that promotes scientific research and contributes to a knowledge-based economy.
Program at a glance
| Item | Details |
|---|---|
| Degree | Master of Science in Clinical Laboratory Sciences |
| Program code | 091404 (Saudi Unified Classification of Educational Levels and Specializations) |
| Location | University main campus, Riyadh — King Saud University |
| Mode of study | On campus (full-time) |
| Study system | Courses and thesis (32 credit hours) or courses and research project (39 credit hours) |
| Duration | 4 study levels |
| Tracks | Medical Microbiology · Medical Biochemistry · Medical Hematology |
Vision and Mission
Leadership and excellence in the specialized fields of clinical laboratory sciences, on a par with peer programs at international universities, in line with Saudi Vision 2030.
To graduate highly competent clinical laboratory specialists, promote scientific research in the field of clinical laboratory sciences, provide proficiency in medical diagnosis, and contribute to a knowledge-based economy to better serve the community.
Program tracks
Each track is offered with two options: a thesis option (32 credit hours) and a course option with a research project (39 credit hours).
Program learning outcomes
Graduates of each track (Microbiology, Biochemistry or Hematology) will be able to:
Program courses
All students take 8 common courses in Levels 1 and 2, then the two courses of their track in Level 3, then the courses of their chosen option.
| Track | Course code | Course title | Prerequisite | Credit hours |
|---|---|---|---|---|
| Medical Microbiology | CLS 513 | Advanced Diagnostic Microbiology | CLS 512 | 3 |
| CLS 514 | Antimicrobial Agents | CLS 512 | 2 | |
| Medical Biochemistry | CLS 533 | Inborn Errors of Metabolism | CLS 532 | 3 |
| CLS 534 | Biochemical Endocrinology | CLS 532 | 2 | |
| Medical Hematology | CLS 543 | Specialized Medical Hematology I | CLS 542 | 3 |
| CLS 544 | Specialized Medical Hematology II | CLS 542 | 2 |
14 required courses (31 credit hours · 96.9%) and the thesis (1 credit hour · 3.1%).
| Level | Course code | Course title | Prerequisite | Credit hours |
|---|---|---|---|---|
| Level 1 | CLS 511 | Diagnostic Microbiology 1 | 3 | |
| CLS 522 | General Pathology | 2 | ||
| CLS 531 | Advanced Methods of Biochemical Analysis | 3 | ||
| CLS 541 | Advanced Medical Hematology | 2 | ||
| Level 2 | CLS 512 | Diagnostic Microbiology 2 | CLS 511 | 4 |
| CLS 532 | Advanced Diagnostic Medical Biochemistry | CLS 531 | 2 | |
| CLS 542 | Advanced Immuno-Hematology | CLS 541 | 2 | |
| CLS 595 | Scientific Writing | 1 | ||
| Level 3 | — | The two courses of the chosen track see the track courses table | 5 | |
| CLS 596 | Thesis Proposal Preparation | Completion of 15 credit hours | 1 | |
| Level 4 | BMT 227 | Introduction to Computer Systems | 2 | |
| STAT 575 | Statistics for Biology | 3 | ||
| CLS 591 | Seminar | 1 | ||
| CLS 600 | Thesis | Completion of 30 credit hours | 1 | |
| Total | 32 |
14 required courses (35 credit hours · 89.7%) and a research project (4 credit hours · 10.3%).
| Level | Course code | Course title | Prerequisite | Credit hours |
|---|---|---|---|---|
| Level 1 | CLS 511 | Diagnostic Microbiology 1 | 3 | |
| CLS 522 | General Pathology | 2 | ||
| CLS 531 | Advanced Methods of Biochemical Analysis | 3 | ||
| CLS 541 | Advanced Medical Hematology | 2 | ||
| Level 2 | CLS 512 | Diagnostic Microbiology 2 | CLS 511 | 4 |
| CLS 532 | Advanced Diagnostic Medical Biochemistry | CLS 531 | 2 | |
| CLS 542 | Advanced Immuno-Hematology | CLS 541 | 2 | |
| CLS 519 | Molecular Diagnostics | CLS 511 | 3 | |
| Level 3 | — | The two courses of the chosen track see the track courses table | 5 | |
| CLS 520 | Clinical Laboratory Management | 2 | ||
| STAT 575 | Statistics for Biology | CLS 512 | 3 | |
| Level 4 | CLS 521 | Infection Control & Biosafety | 2 | |
| CLS 591 | Seminar | 1 | ||
| CLS 595 | Scientific Writing | 1 | ||
| CLS 599 | Research Project | 4 | ||
| Total | 39 |
Course descriptions
The general description of each course, as stated in the approved course specifications.
| Level | Course code | Course title | Course description (as in the approved course specification) |
|---|---|---|---|
| Level 1 | CLS 511 | Diagnostic Microbiology 1 | This course provides an in-depth analysis of major bacterial and viral infections affecting various body systems and explores the epidemiology, risk factors, pathogenesis, and clinical diagnosis of each pathogen. |
| CLS 522 | General Pathology | This course provides the students with advanced theoretical and practical aspects of the causes of cellular stress and the general pathologic responses to cellular stress, the circulatory disturbances, the immune reactions, the main immunopathologic processes and disorders of growth and neoplasia. | |
| CLS 531 | Advanced Methods of Biochemical Analysis | The course gives a detailed knowledge about the principles, instrumentation and application of Spectral techniques. Use of radioisotopes in the clinical labs and their uses in the field of medicine . Provides comprehensive knowledge of Electrophoresis , Chromatography, Immunochemical techniques and Lab automation keeping in mind the needs of the clin laboratories | |
| CLS 541 | Advanced Medical Hematology | This course aims to equip entry level postgraduate students with advanced concepts in haemopoiesis and disorders of blood cells. In particular, pathophysiology and laboratory diagnostic workup of red blood cells disorders, malignant white cells disorders, and hemostasis disorders will be introduced. The course aims also to provide students with the essential knowledge and skills required to competently undertake specialized haematological investigations of haematological disorders in clinical settings. | |
| Level 2 | CLS 512 | Diagnostic Microbiology 2 | This course provides comprehensive knowledge in the spread of pathogens in Mycology, and Parasitology with regards to their structure, pathogenicity, diagnosis and treatment of pathogens significant to public health. Moreover, it covers the immune response made in humans to foreign antigens including microbial pathogens. |
| CLS 532 | Advanced Diagnostic Medical Biochemistry | This course includes, the integration of metabolism , diseases of carbohydrate metabolism, Diabetes. The aspects of Liver, Renal and Bone function, also including, physiology, pathophysiology and lab tests . Further, Endocrinopathies, Clinical enzymology,TDM, tumor markers , Hb parameters are the topics to be taught . | |
| CLS 542 | Advanced Immuno-Hematology | In this course the student will be familiar with the specialized techniques and principles related to blood transfusion. Students will be familiar with and learn through the investigations of incompatible blood and blood products transfusion. Safety techniques in the production of blood and blood products will be taught. | |
| CLS 595 | Scientific Writing | The aim of this course is to clarify the fundamentals of scientific writing and to train students for writing at a higher academic level. The course primarily focuses on writing a graduate level thesis. In addition, it will discuss the different types of scientific papers, how to write scientific manuscripts, literature reviews, and the principles of grant writing. | |
| CLS 519 | Molecular Diagnostics | This course is designed to prepare students for the applications of different molecular biology techniques that are commonly used in molecular diagnostics. These include basic techniques such as nucleic acid and protein extraction, purification, and quantification that will serve as the basis for advanced methods employed in the clinical laboratory. The course also covers fundamental methods in molecular diagnostics which include PCR, array-based technology, and cytogenetics approaches such as karyotyping and FISH. Topics will also cover newly developing molecular techniques such as next generation sequencing and bioinformatics, and their applications in clinical laboratory fields including genetics, oncology, hematology, and the different subspecialties of microbiology. | |
| Level 3 | CLS 513 | Advanced Diagnostic Microbiology | This course provides comprehensive knowledge on the advanced phenotypic and molecular techniques that regularly used in clinical laboratories for the diagnosis of microorganisms, including bacteria, viruses, parasites and fungi. It also covers the basic aspects of sample processing, results interpretation, and troubleshooting. |
| CLS 514 | Antimicrobial Agents | This course provides comprehensive knowledge about antimicrobial therapy and antimicrobial resistance mechanisms. The course also demonstrates laboratory methods and molecular techniques for antimicrobial resistance. | |
| CLS 533 | Inborn Errors of Metabolism | The course is intended to make the student familiar with general concepts about inborn errors of metabolism and newborn screening. It will cover major disorders of carbohydrate and protein metabolism in its biochemical, clinical and diagnostic aspects to include Diabetes mellitus, Pentosuria, Essential fructosuria and Hereditary fructose intolerance, Glycogen storage diseases, Disorders of galactose metabolism, pyruvate kinase deficiency, glucose-6- phosphate dehydrogenase deficiency, disorders of amino acid metabolism, Urea cycle disorders, organic acidaemia and disorders of vitamin B12 metabolism | |
| CLS 534 | Biochemical Endocrinology | This course provides a comprehensive exploration of the endocrine system, with a focus on the in-depth understanding of the hypothalamus, pituitary glands, neuroendocrine hormones, tropic and nontropic hormones. The course explores thyroid functions, hypothyroidism, and hyperthyroidism, then navigates parathyroid glands, calcium regulation, and adrenal glands. Uncover the roles of insulin, glucagon, and gastrointestinal hormones in metabolism. Delve into gonadal hormones, understanding female and male reproductive systems, with a focus on testosterone effects. This helps in gaining a deep understanding of hormonal balance, clinical implications, and practical applications. This course simplifies complex concepts for a clear grasp of endocrinology and reproductive physiology. | |
| CLS 543 | Specialized Medical Hematology I | This course aims to equip postgraduate students with advanced concepts in molecular biology and laboratory diagnostic workup of malignant white cell disorders. The course aims also to provide students with essential knowledge and skills required to competently undertake specialized hematological investigation of hematological malignancies in clinical settings. The course will be (2+1=3) credit hours in which there are 2 contact hours for lectures and one credit hour for practical session including hospital visits of specialized flow cytometry and molecular cytogenetics and genetics labs. | |
| CLS 544 | Specialized Medical Hematology II | This course will cover the basic molecular abnormalities of inheritance, and the normal and abnormal structures and functions of variant hemoglobin’s specifically sickle cell diseases, thalassemia, and other haemoglobinopathies. Abnormalities of red cell enzymes, specifically G6PD enzyme and pyruvate kinase enzyme deficiencies will be highlighted. Mention will be made of Hexokinases and Glutathione reductase enzymes. Emphasis will also be laid on diagnostic criteria including the basic hematological diagnosis and more specific and more modern diagnostic tests including Hemoglobin Electrophoresis, Hemoglobin peptide digestion and chain analysis, Haplotype determination, and enzyme electrophoresis and assay. | |
| CLS 596 | Thesis Proposal Preparation | This course is a practically applied component within the master's program. It plays a crucial role in guiding students through the process of developing their scientific thesis. As one of the initial steps in the research journey, this course helps students formulate a clear and structured research proposal. Through this course, students are equipped with the essential skills needed to define their research questions, establish objectives, conduct literature reviews, and develop a comprehensive research plan. The successful completion of this course is an integral part of the overall program, preparing students for the subsequent stages of their research and ultimately contributing to their attainment of the master's degree. | |
| CLS 520 | Clinical Laboratory Management | The purpose of this course is to provide students with advance understanding of quality management systems and the ever-increasing focus on quality in healthcare. It describes a plan for managing the quality of laboratory’s test results and services using the Quality System Essentials (QSEs). This course introduces students to quality system model that can be applied directly to clinical laboratories. | |
| Level 4 | BMT 227 | Introduction to Computer Systems | The course provides students with the basis for understanding the concepts required to success in using computers practically in healthcare environment. It also covers new applications of computer and informatics in healthcare field. |
| STAT 575 | Statistics for Biology | The course covers various topics in Statistics. It starts with introduction to Bio-Statistics, types of data and graphical representation. Then, it moves to Descriptive Statistics, which includes Measures of Central Tendency (Mean, median, mode) and Measures of Dispersion (Range, Standard deviation, coefficient of variation). After, it introduces Probabilities in detail. Types of random variables then are considered with some statistical distributions and Statistical Inference. Finally, describes regression analysis and analysis of variance (ANOVA) with applying these concepts using statistical software’s such as R, Minitab, Excel, Matlab and SPSS in medical field. | |
| CLS 591 | Seminar | This course covers major and most updated scientific published publications important in CLS/clinical health diagnostics and research. The students will be guided to grasp the knowledge for selecting high caliber publications and discussion of the subject matter through critical analysis, and be enabled/encouraged to practice it by presenting in the presence of audience to reflect the level of learning progress. | |
| CLS 600 | Thesis | The main purpose of this course is to provide the students with skills required to plan, conduct, analyze, and present the findings of the research conducted. They will learn to write a professional research thesis, use library resources and search engines to find suitable journals and articles relevant to their work and extract important information from these. This course will also provide a platform for students to understand the importance of different types of scientific researches and methods of analysis of data. At the end of this course, students should be able to demonstrate the skills required to develop a research proposal, conduct the practical work for the proposed research, assimilate the results, prepare the dissertation of the research conducted and present their findings. | |
| CLS 521 | Infection Control & Biosafety | This course provides an overview of biosecurity/biosafety and the practices, equipment, and facilities for the safe and secure handling of dangerous pathogens in a medical laboratory setting. It is intended for all students looking for or in a medical research, routine hospital laboratory, and any other forms of career that require working in a wet medical laboratory | |
| CLS 599 | Research Project | In this course students work on a research project during the whole semester. Emphasis is placed on efficient utilization of scientific and medical databases, scientific writing, and critical thinking skills. The research project culminates with a written scientific report, an oral defense, and a formal research presentation approved by a judging committee. |
Career opportunities
Professional sectors: health · education · industry and biotechnology.
Thesis and supervision
Admission requirements
In addition to the requirements of the Unified Regulations for Postgraduate Studies in Saudi Universities and King Saud University's implementing rules and procedures for postgraduate studies, the department requires that the applicant: